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Additionally, medications such as saxagliptin and metformin have demonstrated effectiveness in regulating -cell function by reducing inflammation in newly diagnosed T2DM patients with PCOS (74).These findings suggest that the crucial role of pancreatic inflammation and -cell dysfunction in PCOS-related metabolic complications and highlight the need for targeted interventions that can improve -cell function and reduce inflammation

ChIP assay The relevance of ER or ERR transcription factors to the target genes of interest was first queried on their respective ENCODE and ChEA datasets located on Harmonizome 160

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